雌酚酮 Estrone

物理描述 Physical Description

Solid

颜色/状态 Color Form

Small, white crystals, or white to creamy white, crystalline powder

气味 Odor

Odorless

沸点 Boiling Point

445.2 °C

熔点 Melting Point

258-261 °C

溶解度 Solubility

One gram of estrone dissolves in 250 mL of 96% alcohol at 15 °C, in 50 mL of boiling alcohol; in 50 mL of acetone at 15 °C, in 110 mL chloroform at 15 °C, in 145 mL boiling benzene. Soluble in dioxane, pyridine, fixed alkali hydroxide solutions; slightly soluble in ether, vegetable oils.

密度 Density

1.236 g/cu cm at 25 °C

蒸汽压力 Vapor Pressure

2.49X10-10 mm Hg at 25 °C (est)

稳定性/保质期 Stability Shelf Life

Stable in air.

分解 Decomposition

When heated to decomposition it emits acrid smoke and fumes.

其他实验性质 Other Experimental Properties

Crystaline powder. Melts at 190 °C to a liquid which resolidifies and then decomposes at 245 °C. Specific optical rotation: +87.8 deg at 25 °C/D (c = 1 in 0.4% NaOH). uv max (0.04% NaOH): 275, 268 nm (epsilon 838, 851). /Estropipate/

辛醇/水分配系数 LogP

2.6

水溶性 Logs

-3.96

旋光度 Optical Rotation

Specific optical rotation: +158 to +165 deg at 25 °C/D (dioxane)

碰撞截面 Collision Cross Section

164.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]